280Association between acessory gene regulator II expression and mortality among critically ill patients receiving vancomycin for hospital-acquired methicillin-resistant Staphylococcus aureus bacteremia
نویسندگان
چکیده
280. Association between acessory gene regulator II expression and mortality among critically ill patients receiving vancomycin for hospitalacquired methicillin-resistant Staphylococcus aureus bacteremia Regis Rosa, MD, MS; Eduardo Turra; Denise Machado, PhD; Angelica Cechinel; Rodrigo Dos Santos, MD, PhD; Luciano Goldani, PhD, MD; PPG Em Ciências Médicas, Ufrgs Faculty of Medicine, Porto Alegre, Brazil; Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil; Ufrgs, Porto Alegre, Brazil; Hospital de Clinicas de Porto Alegre / Universidade Federal do Rio Grande do Sul, Prto Alegre, Brazil; Infectious Diseases Unit, Hospital de Clinicas de Porto Alegre, Porto Alegre, Brazil
منابع مشابه
Association between Accessory Gene Regulator Polymorphism and Mortality among Critically Ill Patients Receiving Vancomycin for Nosocomial MRSA Bacteremia: A Cohort Study
Background. Polymorphism of the accessory gene regulator group II (agr) in methicillin-resistant Staphylococcus aureus (MRSA) is predictive of vancomycin failure therapy. Nevertheless, the impact of group II agr expression on mortality of patients with severe MRSA infections is not well established. Objective. The goal of our study was to evaluate the association between agr polymorphism and al...
متن کاملIonization failure not due to resistance.
1. González C, Rubio M, Romero Vivas J, González M, Picazo JJ. Bacteremic pneumonia due to Staphylococcus aureus: a comparison of disease caused by methicillin-resistant and methicillin-sensitive organisms. Clin Infect Dis 1999;29:1171–7. 2. Georges H, Leroy O, Alfandari S, et al. Pulmonary disposition of vancomycin in critically ill patients. Eur J Clin Microbiol Infect Dis 1997;16:385–8. 3. R...
متن کاملAdaptation of methicillin-resistant Staphylococcus aureus in the face of vancomycin therapy.
For the past 2 decades, vancomycin has served as the cornerstone of therapy against serious methicillin-resistant Staphylococcus aureus infections. This role is increasingly challenged by questions of efficacy, including reduced efficacy against infections caused by glycopeptide-intermediate S. aureus strains. In an evaluation of clinical glycopeptide-intermediate S. aureus isolates and serial,...
متن کاملMortality among critically ill patients with methicillin-resistant Staphylococcus aureus bacteremia: a multicenter cohort study in Colombia.
OBJECTIVE To evaluate risk factors associated with methicillin-resistant Staphylococcus aureus (MRSA) bacteremia emergence, its prognosis, and mortality-determining factors in critically ill patients in Colombia. METHODS A multicenter, retrospective cohort study conducted in 2005-2008 at 16 public and private reference health care institutions in Bogotá, Colombia, that form part of a national...
متن کاملOutcome and attributable mortality in critically Ill patients with bacteremia involving methicillin-susceptible and methicillin-resistant Staphylococcus aureus.
BACKGROUND Staphylococcus aureus bacteremia carries high mortality rates. The clinical impact of methicillin resistance remains controversial: outcome comparisons between patients with bacteremia involving methicillin-susceptible (MSSA) and methicillin-resistant (MRSA) S aureus are difficult to perform because of important differences in severity of illness. METHODS A retrospective cohort ana...
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عنوان ژورنال:
دوره 1 شماره
صفحات -
تاریخ انتشار 2014